Main variables	No. of employees	Total
No. of companies carrying out R&D in Biotechnology	Fewer than 250 employees	972
No. of companies carrying out R&D in Biotechnology	250 or more employees	69
No. of companies carrying out R&D in Biotechnology	Total	1,041
%Companies according to biotechnology used: Genetic code	Fewer than 250 employees	33
%Companies according to biotechnology used: Genetic code	250 or more employees	45
%Companies according to biotechnology used: Genetic code	Total	34
%Companies according to biotechnology used: Functional units	Fewer than 250 employees	44
%Companies according to biotechnology used: Functional units	250 or more employees	56
%Companies according to biotechnology used: Functional units	Total	45
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Fewer than 250 employees	30
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	250 or more employees	43
%Companies according to biotechnology used: Cellular and tissue culturing and engineering	Total	31
%Companies according to biotechnology used: Bioprocesses	Fewer than 250 employees	52
%Companies according to biotechnology used: Bioprocesses	250 or more employees	74
%Companies according to biotechnology used: Bioprocesses	Total	53
%Companies according to biotechnology used: Sub-cellular organisms	Fewer than 250 employees	10
%Companies according to biotechnology used: Sub-cellular organisms	250 or more employees	17
%Companies according to biotechnology used: Sub-cellular organisms	Total	10
%Companies according to biotechnology used: Bio-computing	Fewer than 250 employees	21
%Companies according to biotechnology used: Bio-computing	250 or more employees	29
%Companies according to biotechnology used: Bio-computing	Total	21
%Companies according to biotechnology used: Nanobiotechnology	Fewer than 250 employees	11
%Companies according to biotechnology used: Nanobiotechnology	250 or more employees	13
%Companies according to biotechnology used: Nanobiotechnology	Total	11
%Companies according to biotechnology used: Other	Fewer than 250 employees	14
%Companies according to biotechnology used: Other	250 or more employees	9
%Companies according to biotechnology used: Other	Total	14
Companies in which biotechnology activities are: Main and/or exclusive	Fewer than 250 employees	504
Companies in which biotechnology activities are: Main and/or exclusive	250 or more employees	20
Companies in which biotechnology activities are: Main and/or exclusive	Total	524
Companies in which biotechnology activities are: A secondary line of business	Fewer than 250 employees	177
Companies in which biotechnology activities are: A secondary line of business	250 or more employees	21
Companies in which biotechnology activities are: A secondary line of business	Total	198
Companies in which biotechnology activities are: A tool necessary for production	Fewer than 250 employees	291
Companies in which biotechnology activities are: A tool necessary for production	250 or more employees	28
Companies in which biotechnology activities are: A tool necessary for production	Total	319
%Company by field(s) of ultimate application of biotechnology use: Human Health	Fewer than 250 employees	45
%Company by field(s) of ultimate application of biotechnology use: Human Health	250 or more employees	58
%Company by field(s) of ultimate application of biotechnology use: Human Health	Total	46
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Fewer than 250 employees	21
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	250 or more employees	9
%Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture	Total	20
%Company by field(s) of ultimate application of biotechnology use: Food products	Fewer than 250 employees	36
%Company by field(s) of ultimate application of biotechnology use: Food products	250 or more employees	33
%Company by field(s) of ultimate application of biotechnology use: Food products	Total	36
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Fewer than 250 employees	24
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	250 or more employees	12
%Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production	Total	23
%Company by field(s) of ultimate application of biotechnology use: Environment	Fewer than 250 employees	17
%Company by field(s) of ultimate application of biotechnology use: Environment	250 or more employees	20
%Company by field(s) of ultimate application of biotechnology use: Environment	Total	17
%Company by field(s) of ultimate application of biotechnology use: Industry	Fewer than 250 employees	16
%Company by field(s) of ultimate application of biotechnology use: Industry	250 or more employees	10
%Company by field(s) of ultimate application of biotechnology use: Industry	Total	15
Personnel in R&D in biotechnology (no. of persons)	Fewer than 250 employees	6,761
Personnel in R&D in biotechnology (no. of persons)	250 or more employees	2,039
Personnel in R&D in biotechnology (no. of persons)	Total	8,800
Personnel in R&D in biotechnology (no. of persons): Researchers	Fewer than 250 employees	3,947
Personnel in R&D in biotechnology (no. of persons): Researchers	250 or more employees	1,177
Personnel in R&D in biotechnology (no. of persons): Researchers	Total	5,124
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Fewer than 250 employees	2,813
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	250 or more employees	862
Personnel in R&D in biotechnology (no. of persons): Technicians and assistants	Total	3,676
Personnel in R&D in biotechnology (no. of persons): women	Fewer than 250 employees	3,743
Personnel in R&D in biotechnology (no. of persons): women	250 or more employees	1,110
Personnel in R&D in biotechnology (no. of persons): women	Total	4,853
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Fewer than 250 employees	2,052
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	250 or more employees	596
Personnel in R&D in biotechnology (no. of persons): (women) Researchers	Total	2,648
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Fewer than 250 employees	1,691
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	250 or more employees	514
Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants	Total	2,205
Personnel in R&D in biotechnology (FTE)	Fewer than 250 employees	4,883.0
Personnel in R&D in biotechnology (FTE)	250 or more employees	1,741.2
Personnel in R&D in biotechnology (FTE)	Total	6,624.1
Personnel in R&D in biotechnology (FTE): Researchers	Fewer than 250 employees	2,899.9
Personnel in R&D in biotechnology (FTE): Researchers	250 or more employees	1,015.7
Personnel in R&D in biotechnology (FTE): Researchers	Total	3,915.6
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Fewer than 250 employees	1,983.1
Personnel in R&D in biotechnology (FTE): Technicians and assistants	250 or more employees	725.4
Personnel in R&D in biotechnology (FTE): Technicians and assistants	Total	2,708.5
Personnel in R&D in biotechnology (FTE): women	Fewer than 250 employees	2,786.8
Personnel in R&D in biotechnology (FTE): women	250 or more employees	989.2
Personnel in R&D in biotechnology (FTE): women	Total	3,776.0
Personnel in R&D in biotechnology (FTE): (women) Researchers	Fewer than 250 employees	1,533.4
Personnel in R&D in biotechnology (FTE): (women) Researchers	250 or more employees	532.3
Personnel in R&D in biotechnology (FTE): (women) Researchers	Total	2,065.7
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Fewer than 250 employees	1,253.5
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	250 or more employees	456.8
Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants	Total	1,710.3
Internal expenditure on R&D (thousands of euros)	Fewer than 250 employees	383,487
Internal expenditure on R&D (thousands of euros)	250 or more employees	154,397
Internal expenditure on R&D (thousands of euros)	Total	537,884
1) By nature of the expense: Current expenses	Fewer than 250 employees	322,844
1) By nature of the expense: Current expenses	250 or more employees	144,698
1) By nature of the expense: Current expenses	Total	467,542
1.1) Remuneration to researchers	Fewer than 250 employees	128,525
1.1) Remuneration to researchers	250 or more employees	53,161
1.1) Remuneration to researchers	Total	181,686
1.2) Remuneration to technicians and assistants	Fewer than 250 employees	62,541
1.2) Remuneration to technicians and assistants	250 or more employees	24,354
1.2) Remuneration to technicians and assistants	Total	86,895
1.3) Other current expenses	Fewer than 250 employees	131,778
1.3) Other current expenses	250 or more employees	67,183
1.3) Other current expenses	Total	198,961
2) By nature of the expense: Capital expenses	Fewer than 250 employees	60,643
2) By nature of the expense: Capital expenses	250 or more employees	9,699
2) By nature of the expense: Capital expenses	Total	70,342
2.1) Land and buildings	Fewer than 250 employees	13,107
2.1) Land and buildings	250 or more employees	1,762
2.1) Land and buildings	Total	14,869
2.2) Equipment and instruments	Fewer than 250 employees	45,130
2.2) Equipment and instruments	250 or more employees	7,266
2.2) Equipment and instruments	Total	52,395
2.3) Acquisition of specific R&D software	Fewer than 250 employees	2,406
2.3) Acquisition of specific R&D software	250 or more employees	671
2.3) Acquisition of specific R&D software	Total	3,077
1) By origin of the funds: National funds	Fewer than 250 employees	338,058
1) By origin of the funds: National funds	250 or more employees	127,492
1) By origin of the funds: National funds	Total	465,550
1.1) Own funds	Fewer than 250 employees	219,919
1.1) Own funds	250 or more employees	95,453
1.1) Own funds	Total	315,372
1.2) From companies	Fewer than 250 employees	29,643
1.2) From companies	250 or more employees	11,517
1.2) From companies	Total	41,160
1.3) Public Administration funds	Fewer than 250 employees	83,279
1.3) Public Administration funds	250 or more employees	19,622
1.3) Public Administration funds	Total	102,901
1.4) From Universities	Fewer than 250 employees	113
1.4) From Universities	250 or more employees	.
1.4) From Universities	Total	113
1.5) From non profit private institutions	Fewer than 250 employees	5,104
1.5) From non profit private institutions	250 or more employees	900
1.5) From non profit private institutions	Total	6,004
1) By origin of the funds: Foreign funds	Fewer than 250 employees	45,429
1) By origin of the funds: Foreign funds	250 or more employees	26,905
1) By origin of the funds: Foreign funds	Total	72,333
2.1) From EU programmes	Fewer than 250 employees	8,588
2.1) From EU programmes	250 or more employees	1,243
2.1) From EU programmes	Total	9,831
2.2) Other foreign funds	Fewer than 250 employees	36,840
2.2) Other foreign funds	250 or more employees	25,662
2.2) Other foreign funds	Total	62,502
Purchase of R&D services in biotechnology (thousands of euros)	Fewer than 250 employees	86,097
Purchase of R&D services in biotechnology (thousands of euros)	250 or more employees	51,898
Purchase of R&D services in biotechnology (thousands of euros)	Total	137,995
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Fewer than 250 employees	65,936
Purchase of R&D services in biotechnology (thousands of euros): In Spain	250 or more employees	40,215
Purchase of R&D services in biotechnology (thousands of euros): In Spain	Total	106,150
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Fewer than 250 employees	20,162
Purchase of R&D services in biotechnology (thousands of euros): Abroad	250 or more employees	11,683
Purchase of R&D services in biotechnology (thousands of euros): Abroad	Total	31,845
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Fewer than 250 employees	52
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	250 or more employees	32
%Companies that consider the following obstacles as very important considering biotechnology development: Access to capital	Total	50
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Fewer than 250 employees	10
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	250 or more employees	7
%Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information	Total	10
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Fewer than 250 employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	250 or more employees	15
%Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources	Total	13
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Fewer than 250 employees	11
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	250 or more employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain	Total	11
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Fewer than 250 employees	17
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	250 or more employees	10
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets	Total	17
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Fewer than 250 employees	17
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	250 or more employees	9
%Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels	Total	17
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Fewer than 250 employees	16
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	250 or more employees	19
%Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception	Total	17
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Fewer than 250 employees	33
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	250 or more employees	32
%Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements	Total	33
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Fewer than 250 employees	49
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	250 or more employees	54
%Companies that consider the following obstacles as very important considering biotechnology development: Time / cost	Total	50
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Fewer than 250 employees	16
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	250 or more employees	13
%Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting	Total	16
% Companies that have requested biotechnology patents in Biotechnology	Fewer than 250 employees	15
% Companies that have requested biotechnology patents in Biotechnology	250 or more employees	23
% Companies that have requested biotechnology patents in Biotechnology	Total	15
Number of patents requested	Fewer than 250 employees	362
Number of patents requested	250 or more employees	59
Number of patents requested	Total	421
% Companies with income of an international origin related to biotechnological activities	Fewer than 250 employees	19.1
% Companies with income of an international origin related to biotechnological activities	250 or more employees	14.4
% Companies with income of an international origin related to biotechnological activities	Total	18.8
% Turnover representing income of an international origin related to biotechnological activities	Fewer than 250 employees	4.40
% Turnover representing income of an international origin related to biotechnological activities	250 or more employees	0.90
% Turnover representing income of an international origin related to biotechnological activities	Total	1.20
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Fewer than 250 employees	37.50
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	250 or more employees	43.30
% Income of an international origin related to biotechnological activities distributed in: Income received from the EU	Total	41.40
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Fewer than 250 employees	62.50
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	250 or more employees	56.70
% Income of an international origin related to biotechnological activities distributed in: Income received from other countries	Total	58.60
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Fewer than 250 employees	93.90
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	250 or more employees	99.80
% Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services	Total	97.80
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Fewer than 250 employees	3.10
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	250 or more employees	.
% Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain	Total	1.00
% Income of an international origin related with activities according to the classification: Operating source abroad	Fewer than 250 employees	1.80
% Income of an international origin related with activities according to the classification: Operating source abroad	250 or more employees	0.10
% Income of an international origin related with activities according to the classification: Operating source abroad	Total	0.60
% Income of an international origin related with activities according to the classification: Other	Fewer than 250 employees	1.30
% Income of an international origin related with activities according to the classification: Other	250 or more employees	0.10
% Income of an international origin related with activities according to the classification: Other	Total	0.50