Main variables;No. of employees;Total No. of companies carrying out R&D in Biotechnology;Fewer than 250 employees;972 No. of companies carrying out R&D in Biotechnology;250 or more employees;69 No. of companies carrying out R&D in Biotechnology;Total;1,041 %Companies according to biotechnology used: Genetic code;Fewer than 250 employees;33 %Companies according to biotechnology used: Genetic code;250 or more employees;45 %Companies according to biotechnology used: Genetic code;Total;34 %Companies according to biotechnology used: Functional units;Fewer than 250 employees;44 %Companies according to biotechnology used: Functional units;250 or more employees;56 %Companies according to biotechnology used: Functional units;Total;45 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Fewer than 250 employees;30 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;250 or more employees;43 %Companies according to biotechnology used: Cellular and tissue culturing and engineering;Total;31 %Companies according to biotechnology used: Bioprocesses;Fewer than 250 employees;52 %Companies according to biotechnology used: Bioprocesses;250 or more employees;74 %Companies according to biotechnology used: Bioprocesses;Total;53 %Companies according to biotechnology used: Sub-cellular organisms;Fewer than 250 employees;10 %Companies according to biotechnology used: Sub-cellular organisms;250 or more employees;17 %Companies according to biotechnology used: Sub-cellular organisms;Total;10 %Companies according to biotechnology used: Bio-computing;Fewer than 250 employees;21 %Companies according to biotechnology used: Bio-computing;250 or more employees;29 %Companies according to biotechnology used: Bio-computing;Total;21 %Companies according to biotechnology used: Nanobiotechnology;Fewer than 250 employees;11 %Companies according to biotechnology used: Nanobiotechnology;250 or more employees;13 %Companies according to biotechnology used: Nanobiotechnology;Total;11 %Companies according to biotechnology used: Other;Fewer than 250 employees;14 %Companies according to biotechnology used: Other;250 or more employees;9 %Companies according to biotechnology used: Other;Total;14 Companies in which biotechnology activities are: Main and/or exclusive;Fewer than 250 employees;504 Companies in which biotechnology activities are: Main and/or exclusive;250 or more employees;20 Companies in which biotechnology activities are: Main and/or exclusive;Total;524 Companies in which biotechnology activities are: A secondary line of business;Fewer than 250 employees;177 Companies in which biotechnology activities are: A secondary line of business;250 or more employees;21 Companies in which biotechnology activities are: A secondary line of business;Total;198 Companies in which biotechnology activities are: A tool necessary for production;Fewer than 250 employees;291 Companies in which biotechnology activities are: A tool necessary for production;250 or more employees;28 Companies in which biotechnology activities are: A tool necessary for production;Total;319 %Company by field(s) of ultimate application of biotechnology use: Human Health;Fewer than 250 employees;45 %Company by field(s) of ultimate application of biotechnology use: Human Health;250 or more employees;58 %Company by field(s) of ultimate application of biotechnology use: Human Health;Total;46 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Fewer than 250 employees;21 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;250 or more employees;9 %Company by field(s) of ultimate application of biotechnology use: Animal Health and Aquaculture;Total;20 %Company by field(s) of ultimate application of biotechnology use: Food products;Fewer than 250 employees;36 %Company by field(s) of ultimate application of biotechnology use: Food products;250 or more employees;33 %Company by field(s) of ultimate application of biotechnology use: Food products;Total;36 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Fewer than 250 employees;24 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;250 or more employees;12 %Company by field(s) of ultimate application of biotechnology use: Agriculture and forest production;Total;23 %Company by field(s) of ultimate application of biotechnology use: Environment;Fewer than 250 employees;17 %Company by field(s) of ultimate application of biotechnology use: Environment;250 or more employees;20 %Company by field(s) of ultimate application of biotechnology use: Environment;Total;17 %Company by field(s) of ultimate application of biotechnology use: Industry;Fewer than 250 employees;16 %Company by field(s) of ultimate application of biotechnology use: Industry;250 or more employees;10 %Company by field(s) of ultimate application of biotechnology use: Industry;Total;15 Personnel in R&D in biotechnology (no. of persons);Fewer than 250 employees;6,761 Personnel in R&D in biotechnology (no. of persons);250 or more employees;2,039 Personnel in R&D in biotechnology (no. of persons);Total;8,800 Personnel in R&D in biotechnology (no. of persons): Researchers;Fewer than 250 employees;3,947 Personnel in R&D in biotechnology (no. of persons): Researchers;250 or more employees;1,177 Personnel in R&D in biotechnology (no. of persons): Researchers;Total;5,124 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Fewer than 250 employees;2,813 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;250 or more employees;862 Personnel in R&D in biotechnology (no. of persons): Technicians and assistants;Total;3,676 Personnel in R&D in biotechnology (no. of persons): women;Fewer than 250 employees;3,743 Personnel in R&D in biotechnology (no. of persons): women;250 or more employees;1,110 Personnel in R&D in biotechnology (no. of persons): women;Total;4,853 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Fewer than 250 employees;2,052 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;250 or more employees;596 Personnel in R&D in biotechnology (no. of persons): (women) Researchers;Total;2,648 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Fewer than 250 employees;1,691 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;250 or more employees;514 Personnel in R&D in biotechnology (no. of persons): (women) Technicians and assistants;Total;2,205 Personnel in R&D in biotechnology (FTE);Fewer than 250 employees;4,883.0 Personnel in R&D in biotechnology (FTE);250 or more employees;1,741.2 Personnel in R&D in biotechnology (FTE);Total;6,624.1 Personnel in R&D in biotechnology (FTE): Researchers;Fewer than 250 employees;2,899.9 Personnel in R&D in biotechnology (FTE): Researchers;250 or more employees;1,015.7 Personnel in R&D in biotechnology (FTE): Researchers;Total;3,915.6 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Fewer than 250 employees;1,983.1 Personnel in R&D in biotechnology (FTE): Technicians and assistants;250 or more employees;725.4 Personnel in R&D in biotechnology (FTE): Technicians and assistants;Total;2,708.5 Personnel in R&D in biotechnology (FTE): women;Fewer than 250 employees;2,786.8 Personnel in R&D in biotechnology (FTE): women;250 or more employees;989.2 Personnel in R&D in biotechnology (FTE): women;Total;3,776.0 Personnel in R&D in biotechnology (FTE): (women) Researchers;Fewer than 250 employees;1,533.4 Personnel in R&D in biotechnology (FTE): (women) Researchers;250 or more employees;532.3 Personnel in R&D in biotechnology (FTE): (women) Researchers;Total;2,065.7 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Fewer than 250 employees;1,253.5 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;250 or more employees;456.8 Personnel in R&D in biotechnology (FTE): (women) Technicians and assistants;Total;1,710.3 Internal expenditure on R&D (thousands of euros);Fewer than 250 employees;383,487 Internal expenditure on R&D (thousands of euros);250 or more employees;154,397 Internal expenditure on R&D (thousands of euros);Total;537,884 1) By nature of the expense: Current expenses;Fewer than 250 employees;322,844 1) By nature of the expense: Current expenses;250 or more employees;144,698 1) By nature of the expense: Current expenses;Total;467,542 1.1) Remuneration to researchers;Fewer than 250 employees;128,525 1.1) Remuneration to researchers;250 or more employees;53,161 1.1) Remuneration to researchers;Total;181,686 1.2) Remuneration to technicians and assistants;Fewer than 250 employees;62,541 1.2) Remuneration to technicians and assistants;250 or more employees;24,354 1.2) Remuneration to technicians and assistants;Total;86,895 1.3) Other current expenses;Fewer than 250 employees;131,778 1.3) Other current expenses;250 or more employees;67,183 1.3) Other current expenses;Total;198,961 2) By nature of the expense: Capital expenses;Fewer than 250 employees;60,643 2) By nature of the expense: Capital expenses;250 or more employees;9,699 2) By nature of the expense: Capital expenses;Total;70,342 2.1) Land and buildings;Fewer than 250 employees;13,107 2.1) Land and buildings;250 or more employees;1,762 2.1) Land and buildings;Total;14,869 2.2) Equipment and instruments;Fewer than 250 employees;45,130 2.2) Equipment and instruments;250 or more employees;7,266 2.2) Equipment and instruments;Total;52,395 2.3) Acquisition of specific R&D software;Fewer than 250 employees;2,406 2.3) Acquisition of specific R&D software;250 or more employees;671 2.3) Acquisition of specific R&D software;Total;3,077 1) By origin of the funds: National funds;Fewer than 250 employees;338,058 1) By origin of the funds: National funds;250 or more employees;127,492 1) By origin of the funds: National funds;Total;465,550 1.1) Own funds;Fewer than 250 employees;219,919 1.1) Own funds;250 or more employees;95,453 1.1) Own funds;Total;315,372 1.2) From companies;Fewer than 250 employees;29,643 1.2) From companies;250 or more employees;11,517 1.2) From companies;Total;41,160 1.3) Public Administration funds;Fewer than 250 employees;83,279 1.3) Public Administration funds;250 or more employees;19,622 1.3) Public Administration funds;Total;102,901 1.4) From Universities;Fewer than 250 employees;113 1.4) From Universities;250 or more employees;. 1.4) From Universities;Total;113 1.5) From non profit private institutions;Fewer than 250 employees;5,104 1.5) From non profit private institutions;250 or more employees;900 1.5) From non profit private institutions;Total;6,004 1) By origin of the funds: Foreign funds;Fewer than 250 employees;45,429 1) By origin of the funds: Foreign funds;250 or more employees;26,905 1) By origin of the funds: Foreign funds;Total;72,333 2.1) From EU programmes;Fewer than 250 employees;8,588 2.1) From EU programmes;250 or more employees;1,243 2.1) From EU programmes;Total;9,831 2.2) Other foreign funds;Fewer than 250 employees;36,840 2.2) Other foreign funds;250 or more employees;25,662 2.2) Other foreign funds;Total;62,502 Purchase of R&D services in biotechnology (thousands of euros);Fewer than 250 employees;86,097 Purchase of R&D services in biotechnology (thousands of euros);250 or more employees;51,898 Purchase of R&D services in biotechnology (thousands of euros);Total;137,995 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Fewer than 250 employees;65,936 Purchase of R&D services in biotechnology (thousands of euros): In Spain;250 or more employees;40,215 Purchase of R&D services in biotechnology (thousands of euros): In Spain;Total;106,150 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Fewer than 250 employees;20,162 Purchase of R&D services in biotechnology (thousands of euros): Abroad;250 or more employees;11,683 Purchase of R&D services in biotechnology (thousands of euros): Abroad;Total;31,845 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Fewer than 250 employees;52 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;250 or more employees;32 %Companies that consider the following obstacles as very important considering biotechnology development: Access to capital;Total;50 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Fewer than 250 employees;10 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;250 or more employees;7 %Companies that consider the following obstacles as very important considering biotechnology development: Access to technology / information;Total;10 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Fewer than 250 employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;250 or more employees;15 %Companies that consider the following obstacles as very important considering biotechnology development: Access to human resources;Total;13 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Fewer than 250 employees;11 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Disconnection from the value chain;Total;11 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Fewer than 250 employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;250 or more employees;10 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of access to international markets;Total;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Fewer than 250 employees;17 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;250 or more employees;9 %Companies that consider the following obstacles as very important considering biotechnology development: Lack of distribution and sales channels;Total;17 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;250 or more employees;19 %Companies that consider the following obstacles as very important considering biotechnology development: Acceptance / public perception;Total;17 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Fewer than 250 employees;33 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;250 or more employees;32 %Companies that consider the following obstacles as very important considering biotechnology development: Legal and regulatory requirements;Total;33 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Fewer than 250 employees;49 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;250 or more employees;54 %Companies that consider the following obstacles as very important considering biotechnology development: Time / cost;Total;50 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Fewer than 250 employees;16 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;250 or more employees;13 %Companies that consider the following obstacles as very important considering biotechnology development: Difficulty accessing patenting;Total;16 % Companies that have requested biotechnology patents in Biotechnology;Fewer than 250 employees;15 % Companies that have requested biotechnology patents in Biotechnology;250 or more employees;23 % Companies that have requested biotechnology patents in Biotechnology;Total;15 Number of patents requested;Fewer than 250 employees;362 Number of patents requested;250 or more employees;59 Number of patents requested;Total;421 % Companies with income of an international origin related to biotechnological activities;Fewer than 250 employees;19.1 % Companies with income of an international origin related to biotechnological activities;250 or more employees;14.4 % Companies with income of an international origin related to biotechnological activities;Total;18.8 % Turnover representing income of an international origin related to biotechnological activities;Fewer than 250 employees;4.40 % Turnover representing income of an international origin related to biotechnological activities;250 or more employees;0.90 % Turnover representing income of an international origin related to biotechnological activities;Total;1.20 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Fewer than 250 employees;37.50 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;250 or more employees;43.30 % Income of an international origin related to biotechnological activities distributed in: Income received from the EU;Total;41.40 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Fewer than 250 employees;62.50 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;250 or more employees;56.70 % Income of an international origin related to biotechnological activities distributed in: Income received from other countries;Total;58.60 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Fewer than 250 employees;93.90 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;250 or more employees;99.80 % Income of an international origin related to biotechnological activities by classification: Internacional trade in products and services;Total;97.80 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Fewer than 250 employees;3.10 % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;250 or more employees;. % Income of an international origin related to biotechnological activities by classification: Milestones, royalties, sale or licensing of technologies outside Spain;Total;1.00 % Income of an international origin related with activities according to the classification: Operating source abroad;Fewer than 250 employees;1.80 % Income of an international origin related with activities according to the classification: Operating source abroad;250 or more employees;0.10 % Income of an international origin related with activities according to the classification: Operating source abroad;Total;0.60 % Income of an international origin related with activities according to the classification: Other;Fewer than 250 employees;1.30 % Income of an international origin related with activities according to the classification: Other;250 or more employees;0.10 % Income of an international origin related with activities according to the classification: Other;Total;0.50